Validate therapies before your first-in-human trials
Are you planning to move your drug candidates into the clinic but you only have animal data?
There are risks to using only animal models, especially in fields like immuno-oncology.
Pear Bio can validate your candidate’s efficacy on fully-human models and give you more confidence before making an IND submission.
Pear Bio uses fresh or viably frozen patient tumor samples to create live 3D cell cultures and validate drug effiacy on a range of phenotypic (cell viabiility, cell migration, etc.) and omic metrics (MSI, immunofluorescence, etc.).
Our immuno-oncology models include matched PBMCs from cancer patients, so you can see the effects of immunotherapy (increased infiltration, more killing by CD8+ T cells, etc.) on patient tumor samples.